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Unpacking the .zip archive:

You will need to unzip the downloaded file in the location you have chosen to hold the executable files (perhaps somewhere like bin). I would NOT put them in Program Files, since spaces in directory or file names and command line environments are a very bad mix, and will cause you endless problems. The archive will create a top level directory Argyll_VX.X.X, where X.X.X is the version number, and the executables will be in Argyll_VX.X.Xbin.

Making the tools accessible:

You should also configure your %PATH% environment variable to give access to the executables from your command line environment.
For Windows 8, 8.1 & 10, look in
Desktop -> Settings -> Control Panel -> System And Security -> System -> Advanced System Settings -> Environment Variables
Libusb.org

For Windows 7, look in
Devices

Start Menu -> Control Panel -> System And Security -> System -> Change Settings -> Advanced -> Environment Variables
For Vista, look in
Start Menu -> Control Panel -> System And Maintenance -> System -> Change Settings -> Advanced -> Environment Variables
For XP and 2000 look in
Start->Settings->Control Panel->System->Advanced->Environment Variables
For NT 4 look in
Start->Settings->Control Panel->System->Environment
You want to add the directory you've chosen to your %PATH%, which is a System Variable. Normally you would add this to the end of the current setting, separated by a ';'.
So if the current value of PATH is '%SystemRoot%system32;%SystemRoot%' and you unpacked Argyll version 1.8.0 in d:bin, then you would modify PATH to be '%SystemRoot%system32;%SystemRoot%;d:binArgyll_V1.8.0bin', - i.e. you append the path to the Argyll binaries to your PATH, separated by the ';' character. The change will take effect when you start a new command shell, which you start from Start Menu->Accessories->Command Prompt, or Start Menu->Programs->Accessories->Command Prompt. You can check that the environment variable has been set by running the command 'echo %PATH%' in the command shell.
The .zip file also contains several useful reference files (such as scanner chart recognition templates, sample illumination spectrum etc.) in the ref sub-directory, all the current documentation in a doc sub-directory, and instrument USB drivers in the usb directory.
NOTE: Vista 64/Windows 7, 8,8.1 & 10 64 bit and Beep prompt: Microsoft (in its infinite wisdom) has removed the built in speaker driver, and now relies on systems having a sound card and speakers's installed and turned on to hear system beeps. So if you're wondering where the beeps have gone when using chartread, now you know.
NOTE: Microsofts generic VGA Driver does not appear to support setting the display VideoLUTs. You will need to install a display driver for your specific display hardware to enable this. Note that it is possible in many cases to use Windows 7 video drivers on Windows 8 systems.

NOTE that if you wish to use Argyll tools (dispwin) to control display calibration, that you will have to disable any other display calibration loader programs.
There are other programs that will interfere with calibration loading, such as igfxpers.exe that gets installed with nVidia 'Optimus' technology.
You may have to disable both the igfx tray module (c:windowssystem32igfxtray.exe) and the igfxpph Module (c:windowssystem32igfxpph.dll) in addition to the persistence Module (c:windowssystem32igfxpers.exe).
A good tool for this is AutoRuns. Note that the igfxpph module may exist in several locations and you have to disable all of them. Reboot after changing settings.

Serial Instruments:

If you are using a serial connected instrument, then there is nothing special to do to enable this.

USB Instruments:

If you are using a USB connected instrument, then suitable USB system drivers may need to be installed.

Note that the Huey, i1 Display Pro, ColorMunki Display and ColorHug colorimeter appears as an HID (USB Human Interface Device Class) device, and hence will be assigned to the default MSWindows HID driver. You therefore don't need to install an Argyll usb system driver for these instruments, although it is possible to select the libusb0.sys driver as an alternative to the default HID driver.
If you are using the JETI specbos 1211, 1201, 1511, 1501 and the Klien K10A then you may need to install the FTDI Virtual COM Port Drivers (VCP), if they are not already on your system. You may have to update to the latest FTDI driver to work with the FTDI FT231XS chip that the JETI specbos 1511, 1501 use.
Jump to your operating system version:
Windows 8, 8.1 & 10
Windows 7
Windows Vista
Windows XP
Windows 2000
Windows 8, 8.1 & 10
Fresh Install of Instrument USB driver:
If you currently don't have any applications that talk to your instrument using USB, then it is relatively simple to use the drivers provided with Argyll, since you don't have to deal with the instrument already having an assigned driver.
Windows 8/8.1/10 does not automatically pop up a 'New Hardware' dialog, so you will have to open the Device Manager manually, and you will also have to temporarily disable UBS driver .inf signature enforcement.
Please NOTE that on some versions of Windows 10, you may have to temporarily disable secure boot in your UEFI BIOS to be able to Disable Driver Signature Enforcement.
To install the Argyll driver for the first instrument:
Settings -> Power -> Hold Shift Key down and click 'Restart' -> Troubleshoot -> Advanced Options -> Startup Settings -> Restart ->
(After Reboot) -> 'Disable Driver Signature Enforcement' (number 7 on the list)
(After system starts, Plug in instrument)
Desktop -> Settings -> Control Panel -> Hardware and Sound -> Device Manager ->
Other Devices -> <instrument being installed> -> right click -> Update Driver Software.. -> Browse my computer for driver software -> Browse..
-> argyllusb folder -> Next -> Install this driver software anyway -> Close
On subsequent installation of other supported instrument types:
Simply plug the instrument in. The Argyll driver will be automatically selected.
Using Argyll drivers with existing OEM drivers:
If you currently have applications other than Argyll accessing your USB connected instrument, then you will have to manually install the Argyll driver, and then switch back and forth between the Argyll and other drivers if you want to switch between applications.
To install the Argyll Driver:
Settings -> Power -> Hold Shift Key down and click 'Restart' -> Troubleshoot -> Advanced Options -> Startup Settings -> Restart ->
(After Reboot) -> Disable Driver Signature Enforcement' (number 7 on the list)
(After system starts, Plug in instrument)
Desktop -> Settings -> Control Panel -> Hardware and Sound -> D

Download Libusb.org USB Devices Driver